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CWD and Venison Sausage: What Hunters Should Know

Short answer:

If your deer came from an area with CWD, have it tested and wait for the result before you grind it. Cooking, smoking and curing do not destroy CWD prions, so the sausage is only as safe as the deer that went into it. CDC says not to eat meat from a deer that tests positive.

Chronic wasting disease is a prion disease of deer, elk and moose. CDC says it has been reported in wild deer in 36 states. Here in Wisconsin it's a fact of deer season. Wisconsin DATCP reports the DNR tested 17,194 samples from April 2018 through March 2019, and 1,063 were positive.

The good news: CDC says CWD infections in people have never been reported. The honest part: it's not known whether people can get it. Wisconsin's Department of Health Services treats it as a precaution and recommends eating venison only from deer where CWD was not detected. For a sausage maker, that comes down to a few habits.

Is it safe to make sausage from a deer shot in a CWD area?

Get the deer tested first. That's the CDC's advice: if you hunt where CWD is present, strongly consider having the deer tested before you eat the meat. And if it tests positive, don't eat it.

Know what the test tells you. Wisconsin DATCP says a "not detected" result doesn't guarantee the deer is CWD free. It means no prions were found in the sampled lymph nodes and the risk is low. Virginia's Department of Wildlife Resources says the same thing: the CWD tests available are not food safety tests. A not-detected result is the best information you'll get, and it's the standard every agency uses.

CDC also says don't shoot, handle or eat a deer that looks sick or acts strangely, or one found dead.

In Wisconsin, the DNR runs sampling through self-serve kiosks, some processors and taxidermists, and at-home kits from local wildlife staff. Check the DNR's CWD pages for this season's locations and whether your county is in an affected area.

Should you wait for the CWD test result before grinding?

Yes. Grinding is the step that matters. Once a deer goes through the grinder, it's in every pound of that batch and on every part of the grinder. A 2025 study published in CDC's journal found that clean venison run through a grinder after a CWD positive deer picked up prions in 5 of 8 trials.

Wisconsin DNR says results typically take 10 to 14 days. That's too long to hold meat in the fridge (2 to 3 days is the limit), so here's the plan:

  1. Bone it out and trim it the way you would for sausage.
  2. Bag it by deer. One deer per bag, never mixed. Write the date and the test barcode or tag number on every package. Virginia's agency recommends marking every package so meat from a positive deer can be found and pulled.
  3. Freeze it at 0°F or below.
  4. Grind after the result comes back. Thaw in the refrigerator, never on the counter.

Thawing and refreezing as sausage is fine. Nebraska Extension, citing USDA, says meat thawed in the refrigerator is safe to refreeze without cooking, with some loss of quality. Grinding and stuffing it partly frozen actually helps keep the fat from smearing.

The backstraps and roasts can go in the freezer the same way. They just don't need the grinder, so a positive result only costs you those packages.

Does cooking or smoking kill CWD prions?

No. This is the part people get wrong, because heat fixes almost every other meat problem.

StepKills bacteria?Destroys CWD prions?
Smoking to 152 to 160°F internalYesNo
Cure #1 or Cure #2HelpsNo
FreezingStops growthNo
Normal cooking, 180 to 500°FYesNo (Wisconsin DATCP)
Incineration, about 1800°FYesYes

Wisconsin DNR puts it simply: prions are not destroyed even when cooking meat to safe temperatures. Your smoker can't fix a positive deer, and neither can curing or drying. That's the opposite of trichinella in bear and wild hog, where cooking to temperature is exactly the fix. With bear and hog, heat is the answer. With deer, testing is.

Why does processor sausage mix deer together?

Sausage takes volume. A lot of processors make it in big batches, and a batch can hold trim from many hunters' deer. That's a practical way to run a shop, and it's why the agencies tell you to ask how yours handles it.

CDC says that if your deer is processed commercially, ask to have it processed individually so you're only getting meat from your animal. Wisconsin DNR suggests asking whether the processor mixes meat from untested animals. Wisconsin DATCP notes that processors can batch deer with "not detected" results together on cleaned and sanitized equipment.

Making your own sausage settles the question. Your deer, your test result, your batch. It doesn't matter if you end up with 7.4 lb of trim or 31 lb. The recipes in the DeepWoodz app scale to the exact weight you have, with the cure locked safe, so one deer makes one batch.

What parts of a deer should you avoid when trimming for CWD?

Wisconsin DATCP says the highest concentrations of CWD prions are in the lymph nodes and nervous tissue. Prions have also been found in blood, muscle and fat, so no part of a positive deer counts as prion free. That's why the test comes first and the trimming habits come second.

From Wisconsin DNR and CDC:

How do you clean a meat grinder after a CWD positive deer?

Wisconsin DNR's steps:

  1. Wash all knives and equipment with soap and water to remove all organic material, and rinse with water.
  2. Soak for an hour in a 50/50 solution of bleach and water. For stainless steel items, soak for a minimum of five minutes.
  3. Wipe down counters and work areas with the same 50/50 bleach and water solution, and let them air dry.

Wisconsin DATCP adds two details for processors that are worth copying at home: use bleach that is at least 6% sodium hypochlorite (check the label), and after the soak, rinse everything with clean hot water to limit chlorine damage.

Do step 1 properly. Bleach can't get through bits of meat and fat, and soap alone doesn't do the job either. The 2025 study in CDC's journal found dish soap did not reliably clean prions off grinder parts, while bleach did. It found the residue on the plate and cutter and on the ring threads, so take the grinder fully apart. Don't run another deer through it until it's been through all three steps.

Bleach is hard on aluminum and some other metals, so check the maker's care instructions on any part that isn't stainless.

What do you do with venison from a CWD positive deer?

Don't eat it. CDC, Wisconsin's Department of Health Services and Virginia's wildlife agency all say the same.

The recipes in DeepWoodz are free, and they scale to the exact weight of the one deer you tested, whether that's a yearling doe or a big-bodied buck. The cure is worked out from your meat weight and locked safe.

Bottom line

Test it, bag it by deer, freeze it, and grind after the result. Cooking and smoking won't make a positive deer safe, so the test is the only real check you've got. Bone out instead of sawing through the spine, trim the fat and lymph nodes, and if one ever comes back positive, toss the meat and give your grinder the full soap, bleach and rinse treatment.

Before you get to the grinder, read how long a deer can hang, and when you're ready to cure it, how much Cure #1 per pound (0.25% of meat weight, 156 ppm).

Common questions

Is it safe to make sausage from a deer shot in a CWD area?

Get the deer tested first. CDC says to strongly consider testing a deer from an area with CWD before you eat the meat, and not to eat meat from an animal that tests positive. No human case of CWD has ever been reported, but it has not been ruled out, so health agencies treat it as a precaution.

Does cooking or smoking kill CWD prions?

No. Wisconsin DATCP says no temperature in the normal cooking range, 180 to 500°F, is known to inactivate CWD prions. It takes incineration at about 1800°F. A smoker, a pan, a cure or a dehydrator will not make a positive deer safe.

Should I wait for CWD test results before grinding?

Yes. Grinding is where one deer gets into every pound of the batch and into your grinder. Bone out the meat, bag and label it by deer, freeze it, and grind after the result comes back. Wisconsin DNR results typically take 10 to 14 days.

How do you clean a meat grinder after a CWD positive deer?

Wisconsin DNR says to wash everything with soap and water to remove all organic material and rinse, then soak it in a 50/50 solution of bleach and water for an hour. Stainless steel items need a minimum of five minutes. Wipe counters with the same 50/50 solution and let them air dry. Wisconsin DATCP adds: use bleach that is at least 6% sodium hypochlorite, then rinse with hot water.

What do you do with venison from a CWD positive deer?

Do not eat it. Wisconsin DNR says unwanted carcass waste or packaged meat should go to a landfill that accepts it. In Wisconsin, a positive result also puts a replacement harvest authorization in your GoWild account.

What parts of a deer should you avoid because of CWD?

Wisconsin DNR says to minimize contact with the brain, spinal cord, spleen and lymph nodes, and not to cut through the spinal column except to remove the head. Bone out the meat and trim away fat and connective tissue, which also removes the lymph nodes.

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